Important Safety Information

Start your Keveyis Journey

Starting your KEVEYIS journey

Implementing a treatment plan is a move in the right direction. KEVEYIS can help you gain greater control over PPP episodes. It’s proven to reduce the number, severity and length of PPP episodes.1,2

Get the most out of your treatment

Keep in mind that everyone’s treatment journey is different, and it may take some time to find the right KEVEYIS dose.1
How to talk to your doctor about PPP

To get the most out of your treatment, remember the 3 T’s:

Take

Take your prescribed amount every day. Avoid skipping doses, which can lead to episodes of muscle weakness and/or temporary paralysis. If you miss a dose, take your next dose as scheduled.

Track

Track your episodes and how they change using the Daily Tracker Tool. This will help your doctor determine if you’re taking the right amount.

Talk

Talk regularly with your doctor to ensure KEVEYIS is working for you. It’s normal for your doctor to increase or decrease your dosage, especially in the first 9 weeks.2
How to talk to your doctor about PPP

Stay with it

KEVEYIS is a long-term treatment meant to be taken daily. Reach out to your doctor or our Patient Access Managers at any time on your KEVEYIS journey for support.

In clinical studies, people noticed benefits of taking Keveyis as they saw continued reduction of their attacks at 1 year.2*

*The double-blind, placebo-controlled study of 9 weeks (N=65) was followed by a 1-year, open-label extension phase (N=58) in which all participants received KEVEYIS. The number, severity and duration of PPP attacks were assessed from weeks 2 to 9 of the double-blind, placebo-controlled study and during weeks 54 to 61 of the 1 year open-label extension.2

PATIENT TESTIMONIAL

“Having better control over my PPP symptoms has meant I can engage more fully in my life. I can babysit my beautiful granddaughter, go out with friends, and have more independence. I worry much less now about falling or having to be rushed to the hospital.”

—Janine, KEVEYIS Patient and PPP Mentor

KEVEYIS common side effects1

It’s normal to experience certain side effects when you start taking KEVEYIS. Some side effects can be resolved with proper techniques or dose adjustment with the help of your doctor.1

Tingling or prickling sensations
(pins and needles)

Confusion or trouble paying attention

Changes in taste

Brain fog

PPP MANAGEMENT

Set treatment goals and track progress

Setting treatment goals with your doctor is a great way to track your progress while on treatment.

Treatment goals should be specific to you and could include:

  • Participating in an activity you enjoy
  • Going back to work
  • Traveling
 

Use the Daily Tracker Tool to stay on top of your PPP management. Remember to keep your healthcare providers informed of your progress and any side effects.

Get started on Keveyis

COMPLIMENTARY SUPPORT

Speak with people who understand

PPP MentorConnect™ can put you in touch with another person taking KEVEYIS who may understand what you’re going through. Whether you’re an adult with PPP or a caregiver of someone with PPP, you can connect with someone who gets it.

By submitting this form, I understand I am giving Xeris Pharmaceuticals, Inc., its affiliates, and business partners permission to use the personal information provided in this registration form to contact me by the following methods, but not limited to: mail, email, telephone call or in-person about disease and product information, disease or product-related events, support services, market research, and to share promotional and marketing information. By submitting this form, I consent to these uses and am confirming that I have read and agree to the Xeris Pharmaceuticals® Terms of Use and Privacy Statement. I understand I can unsubscribe by clicking on the unsubscribe link in future communications or by sending a letter with my full contact information (eg, name, address, email, phone, etc) to Xeris CareConnection™ Patient Support Services, 1375 W Fulton Street, Suite 1300, Chicago, IL 60607.

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References

  1. KEVEYIS [package insert]. Chicago, IL; Xeris Pharmaceuticals.
  2. Sansone VA, Burge J, McDermott MP, et al; for the Muscle Study Group. Randomized, placebo-controlled trials of dichlorphenamide in periodic paralysis. Neurology. 2016;86:1408-1416.

INDICATION AND IMPORTANT SAFETY INFORMATION — READ MORE

Indication and Important Safety Information

 

What is KEVEYIS?

KEVEYIS (pronounced keh-VAY-iss) (dichlorphenamide) is a prescription drug used to treat primary hyperkalemic periodic paralysis, primary hypokalemic periodic paralysis, and other similar diseases.

 

What should you tell your healthcare provider before taking KEVEYIS?

Tell your doctor if you are allergic to dichlorphenamide or other sulfa drugs; if you take high doses of aspirin, or if you have lung or liver disease; if you are pregnant, plan to become pregnant, or are breastfeeding or plan to breastfeed.

 

What should you know about KEVEYIS?

  • Severe allergic and other reactions have happened with sulfonamides (drugs such as KEVEYIS) and have sometimes been fatal. Stop taking KEVEYIS at the first sign of skin rash, swelling, difficulty breathing, or any other unexpected side effect or reaction, and call 911 right away.
  • Tell your healthcare provider if you take aspirin or if another healthcare provider instructs you to begin taking aspirin. High doses of aspirin should not be taken with KEVEYIS.
  • KEVEYIS can cause your body to lose potassium, which can lead to heart problems. Your healthcare provider will measure the potassium levels in your blood before you start treatment and at certain times during treatment.
  • Tell your healthcare provider about all other prescription and over-the-counter medicines you take, including supplements, as some medicines can interact with KEVEYIS.
  • While taking KEVEYIS, your body may produce too much acid or may not be able to remove acid from the body. Your healthcare provider may run tests on a regular basis to check for signs of acid buildup.
  • KEVEYIS may increase your risk of falling. Tell your healthcare provider right away if you experience a fall while taking KEVEYIS.
  • The risks of falls and acid buildup are greater in elderly patients.
  • It is not known whether KEVEYIS is safe or effective for people younger than 18 years of age.

 

What are the most common side effects with KEVEYIS?

The most common side effects are a feeling of numbness, tingling or burning (“pins and needles”) in the toes, feet, hands or fingers; trouble with memory or thinking; feeling confused; and unpleasant taste in the mouth.

These are not all of the possible side effects of KEVEYIS. Call your healthcare provider for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Full Prescribing Information.

Xeris

Keveyis®, Xeris Pharmaceuticals®, Xeris CareConnection™, PPP MentorConnect™, and their associated logos are trademarks owned by or licensed to Xeris Pharmaceuticals, Inc.

FOR PATIENTS

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Copyright © 2024 Xeris Pharmaceuticals, Inc. All rights reserved.
US-KEV-24-00031 7/2024

Find answers

Take the next step

Get customized support for your KEVEYIS journey. Simply fill out the information and a Patient Access Manager will contact you. They will walk you through the entire process, from diagnosis to treatment and beyond.

By submitting this form, I understand I am giving Xeris Pharmaceuticals, Inc., its affiliates, and business partners permission to use the personal information provided in this registration form to contact me by the following methods, but not limited to: mail, email, telephone call or in-person about disease and product information, disease or product-related events, support services, market research, and to share promotional and marketing information. By submitting this form, I consent to these uses and am confirming that I have read and agree to the Xeris Pharmaceuticals® Terms of Use and Privacy Statement. I understand I can unsubscribe by clicking on the unsubscribe link in future communications or by sending a letter with my full contact information (eg, name, address, email, phone, etc) to Xeris CareConnection™ Patient Support Services, 1375 W Fulton Street, Suite 1300, Chicago, IL 60607.

Thank you!

We’ve received your message and will be in touch shortly.